1.4.2 Bioelectronics with Organic Semiconductor

Organic semiconductors have proven to be an excellent candidate for flexible and

stretchable bioelectronic applications, particularly in biosensors and biomedical devices,

due to a combination of their low-temperature solution-phase processability, good me­

chanical deformability, and applicable charge transport properties. Organic bioelectronics

that is mechanically compliant, whether in contact with the skin or implanted into tissues,

can aid to lessen discomfort and other negative outcomes that can arise as a result of the

mechanical mismatch between the device and the body [34]. Furthermore, because many

organic semiconductors are self-healing and biodegradable, they are particularly well

suited for use in wearable and injectable bioelectronics applications, such as cardiac

monitoring. It will be necessary to consider many variables when developing the next

generation of organic bioelectronics, including the balance between mechanical deform­

ability and device mobility, long-term stability under physiological conditions, stretching

and bending durability, among other things [35,36].

On the other hand, surface functionalization may also be utilized to produce

bio-recognition (Figure 1.5a, b) [37]. Mulla et al. [38] employed monomeric porcine

odorant-binding proteins (pOBPs) as ligands in a capacitive coupled p-type organic FET

FIGURE 1.4

(a) The illustration of coaxial p-type/intrinsic/n-type (p–i–n) Si-NWs architecture for photo-electrochemical

extracellular modulation of neuron membrane potential. Reproduced with permission [ 27]. Copyright (2018),

Springer Nature. (b) The tomographic representation of atomic probe of diffused gold on Si-NWs architecture’s

sidewalls. Reproduced with permission [ 31]. Copyright (2018), Springer Nature. (c) TEM/SEM images showing

the cross-section along with diffraction pattern of Si-NWs architecture. Reproduced with permission [ 32].

Copyright (2018), Springer Nature.

Introduction to Bioelectronics

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